Hi,
When started working with a simple Flask application @work that uses ERS i found a really great module on github.
But it wasn't compatible with our 2.2.x, so I updated it with json calls and 2.2.x compability.
If you want to take it for a spin, and check if there are any fugly bugs or (probably) missing features 
GitHub - falkowich/ise: Python module to manage Cisco ISE via the ERS API
Next step is to get it more test done with wiremock and nose2.
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Regards Falk
